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1.
A term used for someone who is known to have had numerous plastic surgeries to enhance their looks when considering the face.
John: Damn Nick, Ashley's becoming quite the Mrs. Potato Head with that nose job.

Nick: yeah...now if only she'd do something about those small tits
by Dannnyyy June 15, 2013
 
2.
When one pours french fries on their penis and asks for a blow job from their partner.
My girlfriend gave me a Mrs. Potato Head last night.
by HimInMeDickIt March 22, 2010