An unofficial medical condition, whereby the hand used to control the mouse on a PC becomes cold, yet the other hand of the user remains at normal temperature.
Many players experience mouse hand during a long gaming session online.
by Loop Goose July 21, 2005
The chilling sensation that effects a person's right hand when they have been using a computer mouse for extended periods of time in a cold room and/or during winter.

Mousehand can include numbness, turning blue, lack of movement and can extend up the right arm as far as the shoulder region.
It's so fucking freezing and now I've got mousehand!
by firespook July 08, 2009

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