The longest river in the United States. It has historically been a major transportation artery for goods and people. The name is Algonquin for "big river."
The largest river in North America, which runs from Northern Minnesota to the Gulf of Mexico.
or, for the pervs, the area between the breasts on a woman
2) on their first date, he begged to lick her Mississippi River... but she refused (what a gaywad, that guy was)