Top Definition
(Adj.) The gastronomic compensation of continuous stimulation of the "old factory". In terms of "Mike-and-Ikey" It is the successive contrast (or fatigue) of sweet, salt, sour, bitter, and umami, with the physical adaptation of chewing the gummie candy.
"I turn around and see that Edward is eating a bag of Mike-and-Ikes."

"How are thoes Mike and Ikes treating ya'?"

"Their Mike-and-Ikey"
by TheJerseyGiggleBunny September 08, 2009

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