Top Definition
An angry, possibly magical, woman who is either addicted to, selling, or in possession of methamphetamines. Will occasionally lace brownies with meth and offer them to small children.

Also a derogatory term towards women and witches alike.
Awww... That poor child! I wonder how he got addicted to meth?
Well, his mother is a methwitch.

My girlfriend is being a total methwitch!
by imnotababyimatumor October 21, 2011
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