Top Definition
That tired sensation that sets in right after eating fast food. Gives a feeling of a deep sleep coming on. Originated from McDonalds, but applies to almost any fast food restaurant.
guy 1:Oh man, I just ate a ton of McDonalds. I feel a total McComa coming on.

guy 2: Oh, I know what you mean! I fell into such a McComa the other day after I ate at Jack in The Box.
by sexyseabass July 21, 2010

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