Top Definition
The profound indigestion one feels directly following a meal at McDonalds. This feeling is compounded by the self esteem drop that occurs simultaneously after realizing how much fast food you just ate.

Strangely, young men aged 13-22 seem to be unaffected by this medical issue.
Dude, I'm not feeling so well after those six McRibs.

Don't worry about it man, It's just the Mc-gestion kicking in.
by Cranky old piece of cheese November 09, 2010
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