Being addicted to the video game series Mass effect by Bioware.

By reading the books, owning a item of Mass effect, or playing the game more than 6 times.
Jake keeps saying that, "Mass effect will suck you in like a black hole!"

He is Mass effected.
by BigJK May 15, 2011
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An evil game that will eat your soul if you try it.

It is for the Xbox360, and it is Evil.
-"Mass effect ate my soul."
-"l0lw00t it are 3vul lawl!"
by Vallzing January 4, 2008
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The aftermath of a night of playing sci-fi role playing game Mass Effect or Mass Effect 2 for the Xbox or PC. This is usually the result of playing more than 4 hours at a time or playing until the sun rises. Symptoms include falling asleep at work or just being disoriented throughout the day. Can alter sleep patterns and cause slurred speech. If this pattern of late night gaming persists it could lead to altered perceptions of reality where you want to make decisions like Commander Shepherd or make constant references to the game in conversations with people who have no idea what you are talking about.
Example 1
Guy1: Hey man I tried to call you around 2pm why didn't you answer?
Guy2: Oh sorry I was suffering from Mass Effect effect and was still sleeping

Example 2
Guy1:Hey where were you last night?
Guy2:Oh sorry I was out with a friend you don't know
Guy1: (grabbing his shirt and slamming guy2 against the wall) Why don't you stop jerking me around and give me some answers
Guy2: Whoa relax "Commander Shepherd" I think you're suffering from the Mass Effect effect

Example 3
Guy1:Man my girlfriend thinks about sex more than most guys do, I swear she's part Asari!
Guy2:What the hell is an Asari?
Guy1:Or sorry man, I'm suffering from Mass Effect effect
by Changus Kahn February 2, 2010
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The sequel to possibly the most epic game ever. It in it's self will be an legendary game.
DudeREuse I can't wait to play Mass effect 2 it looks soooo awsome!!!
by Theultimategamer January 17, 2010
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The 3rd and final installment in the mass effect series. "Im commander shepard and this will be the greatest game in the world." is it march 6th yet?!

Mass effect 1-Reapers?
Mass effect 2-Ah yes, "Reapers"
Mass effect 3- OH SHIT REAPERS!
open minded gamer) dude did you hear about mass effect 3 coming out next march?

idiot gamer) yea its gonna suck, all combat and no rpg elements.

open minded gamer) *rolls eyes*
by Jimonster22 December 24, 2011
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When someone discusses an amazing game around you, giving you the urge to play said game
Pete: Oh I always play as Male Shepard in Mass effect. So I can bone Tali.

Sam: aw shit. Now I’ve got the Mass Effect effect.
by Pogoextreme June 13, 2018
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A game depicting the expulsion of non-whites from the Milky Way Galaxy to Andromeda so the SJW brigade can ruin that galaxy too. Exclusive features include shit animation, no white skin options (Thanks Manveer Heir), but more diversity than a college advertisement.

Mass Effect Andromeda: Fuck white people and fuck aliens.
1) Mass Effect Andromeda really helped me with my Diversity Studies class.

2) Mass Effect Andromeda let me make a transgender krogan have sex with a cisgender asari transvestite male in the ass.
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