look up any word, like pussy:
 
11.
A sound effect to describe almost any situation
Person 1: and then I was like....are you listening to me?!
Person 2: mano..... (darty eyes)
by Crendy September 20, 2007
 
1.
Short for Hermano, which means brother in Spanish.
Hey, you want a cold beer mano?
by Egyptian Magician June 30, 2005
 
2.
hands, of the fate varity
"Manos" the Hands of Fate
by DarkMatter October 06, 2004
 
3.
odd, weird, out of the norm, creepy, mysterious, outlandish, ridiculous, and unusual; something seen as being in "the hands of fate." As made popular by MST3K.
"The other day, on a whim, my friends and I decided to kill a goat. We used a rock and it took eight tries. It sounded fun at first, but turned out to be manos."

by Thel200ster March 18, 2007
 
4.
King of the Internet.
23:11 <Manos> The last time I had pussy, it was awesome.
23:12 <willyg> yea
23:12 <Manos> This was YESTERDAY.
23:12 <willyg> it always is
23:12 <electronarcosis> cool
23:12 <Manos> And it was with 3 different women.
by mancharmer June 29, 2009
 
5.
is a slang for irmão, which means brother in Portuguese.
hey mano let's pick up some chicks
by sacht March 11, 2014
 
6.
An expression used to show deep love, usually used for cute & adorable people. Frequently used by love-birds to express how they feel towards each other.
You're so adorable, can i call you my mano?
by Chullbulla November 23, 2013
 
7.
Slang for good friend or person you have known a while and bonded with ( Mano - male ) ( mana - female ) originated from the Spanish slang of hermano (brother) someone you are close to. Popular between 2 people that originate from seperate countries. I.e Britain and Spain
Hey, Mano!

Hey!
by ENG.DICT July 08, 2012