Top Definition
An STD combination thought to have originated in the Northeast US by a woman named Mandi, who worked as a janitor. The term combined the names Mandi and Cinderella, and the STD's include but are not limited to: Chlamydia, Herpes, Crabs, and Syphilis.
Dude, I hope you wrapped it up, that chick looks like she's got Manderella!
by FearFree1 October 28, 2010

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