Top Definition
A fictional product used in phrases in which you intend to challenge someone's manhood, best used in a voice dripping with sarcasm.
Example 1:
Walter: *screams* A wasp just flew right in my face!
Steve: Sh*t mate, maybe you'd like some man up cream to go with that scream?

Example 2:
Walter: Yeah I've been kept awake for about three nights because of my throbbing foot, I stepped on a pin!
Dave: Yeah buddy you might wanna try putting some man up cream on that sh*t.....
by a tru LAD August 09, 2011
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