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1.
acronym for "move the fuck out"; describes a fully grown man with no mental nor physical disabilies (save maybe being a virgin and having a large nose--but otherwise fully able to support himself) who still lives with his parents without paying major contributions for his living status.
You're 25 and still live with your parents? You need to MTFO!
by anonymous January 14, 2004
 
2.
Move the fuck on
He left you six years ago MTFO
by Heyku guy January 12, 2014
 
3.
Make The Fuck Out.
1)Intense making out,
2)A neccessary statement made to attractive females at the bar/club/houseparty/street.
1)So did you just make out with her, or did you MTFO?
2)MTFO, BITCHES!
by Blessing November 01, 2007