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1.
An "M DOT" is a nick name for a crazy, tough, risk taking person. It's a way to describe someone in a fierce and violent way.
Yo, that dude right there is M Dot, you don't wanna get it poppin with him ...
by D MARVEL0USS July 18, 2008
 
2.
A m dot is the conscious placement of DNA'd aura on the DNA of another person's body, to protect, direct and inform, it must be age appropriate and consensual on the part of all parties involved.
Is that a m dot or a parasite?
My m dot from a friend told me the answer.
by tbdeity April 25, 2014
 
3.
a colloquialism often used as a stage pseudonym for short, squatty, half jewish rappers. subject to various changes, e.g. mdizzle, mdottie2hottie, etc.
Person 1: Wow, did you see that gentlemen lay down those phatty fresh rhymes atop that stage over yonder?

Person 2: Yessir I did. I believe he goes by mdot, but I have also heard him referred to as mdottie2hottie.
by igotyou May 08, 2005