Top Definition
When sitting on the toilet, the Lukehole is the space created by your legs, genitals and the outer edge of the toilet.
Karen sat on the toilet as Frank waited outside the stall; they both had to pee. Karen says, "Why don't you come in here and pee in my Lukehole, so we can go together?"
by BloodBathandBeyond September 09, 2010

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