a nickname for the greatest heavyweight boxer of all time Muhammad Ali given to him because hes from Louisville, Kentucky and he had a big mouth which he always backed up.
The Louisville Lip always taunted "Smokin" Joe when they fought in a attempt to aggravate the hell out of him.
by Mandelas Discple September 23, 2007
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After you get finished violating a girl from the pooper, take you shit covered dick and rub it on her lips as if applying lip gloss.
Chris gave Ashley some Louisville Lip Gloss and she looks good!
by atoevan September 19, 2008
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