Top Definition
To get drunk with friends.
CM: Hey yo! lets get lost in space this weekend!

SJ: Sounds good!

DG: Im Lil Wayne and im lost in space!
by Arab Money 802 June 09, 2009
to have sexual intercourse with a woman with an exceptionally large/loose vagina
"blimey sean" "I thought kev's next door neighbour was quite tasty 'til i gave her one - no good - lost in space"
by theWestHamfan December 10, 2003
When a guys dick is so small it practically gets lost in your cooch.
Wow, I didn't know Jhon was so small. Last night we finally did it and he got lost in space.
by x3 x3 November 10, 2005
Synonym for someone who is either high or suffering from a delusion. From the 1960s television series "Lost in Space" where a group of travelers found themselves stranded on an alien world.
That guy is truly lost in space. He's out of it.
by EmperorNorton47 April 24, 2015
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