Top Definition
Pronounced (LOOZ-bie-un):

A loser lesbian.
A lesbian who just CAN'T seem to get laid, or get a date, or find a lover. Chicks always escape her.
Jess (a lesbian): Damn! My luck with chicks is HORRIBLE.

Alice: Mmm...You'd think being a lesbian, it'd get you some vag!

Jess: I guess I'm not a true lesbian then...I must be a losebian. =(

or

Lucy (a lesbian): What the FUCK!?
I just got rejected by that girl...

Liz: Girl, I hate to break it to ya...but you're a losebian. =/
by EmjayBAH June 19, 2010

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