Top Definition
1. A familiar way to reference to your, or someone elses son or younger male sibling.
2. A less obvious way of describing a gram or small amount of drugs.
"I took the little guy to a baseball game."
Person A:"What are you looking for?"
Person B:"Just a little guy tonight."
by Turkey151 January 09, 2008
So what are you going to do tonight, stay in and beat up the little guy?
by dr. shango August 02, 2003
Refering to a person at the bottom.
Example: you have a ladder and you are at the bottom of it, but need to be at the stop.
The little guy has to work his way up in life to make it to the top!
by the actor May 13, 2011
street slang for a roxicodone 30 mg instant release pill.

slang for an roxy on long island, new york.
user- "lemme get a little guy"
dealer- "i got u..20 bills"
by thatOCguy February 23, 2010
Somebody who is pouting and inconsolable over something trivial. Acting stubborn and pessimistic like a small child who is throwing a tantrum.
"Don't even bother talking to him. Robby's being a Little Guy today."
by MookyTheCat August 10, 2009
just another word for semen
I shot little guys all over the sheet last night.
by AD November 11, 2004
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