Top Definition
Also known as "LFS."

The medical condition which takes place immediately as you consume your last fast food french fry, which involves the instantaneous feeling of digestive failure as you place the last fry in your mouth.
Hungry friend: "Man, are you done with those fries??"

Fry Eater: "Yeah man, I just ate the las -- oh no...I'm getting some serious LFS!!!"

Hungry friend: "Dang, you got Last Fry Syndrome!"
by PJoBro December 08, 2009

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