Opioid withdrawal that is brought on by abuse of the plant Mitragyna Speciosa (otherwise known as kratom).

Kratom contains the naturally occuring drugs Mitragynine and 7-OH-Mitragynine, both of which are mu-opioid agonists. Because of this activity on opioid receptors, this herbal drug induces short but euphoric highs as well as a pretty nasty withdrawal if use is discontinued after a few months of daily usage. This withdrawal is known as “Kratom flu.”

Some users say it isn’t as bad as the dope flu you get from oxy or heroin, some say it’s worse. In my experience it’s pretty shitty either way.
Friend: Why are you yawning bro?

Me: My state made mitragynine a schedule I controlled substance so I think I’m coming down with the kratom flu.

Friend: Try ordering some tianeptine because that’s somehow still perfectly legal!
by danasp_42 December 7, 2021
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