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1.
Often used by groups of girls as a way to praise someone's actions. Either that or they literally mean they will kill you.
"Ooh, sharkquisha! Kill em!"

Or
"Let's kill em."
by Mardezrealgirl January 12, 2014
 
2.
a phrase used often in oldham social circles, particularly at hotel woodhouse, many plots to 'kill em' are generally thought up when everyone is on pills.
'lets go and kill em'

'kill em'

'em em em em em'
by boothyboothyboothyyy July 10, 2008