Itchy mouth has a similar meaning like big mouth. It means someone can't stop gossiping or likes to kick up a fuss. It's very common among high school students and 1st year university students.
"Hey pork pie, you need to see a doctor for your itchy mouth!"

"I'm sorry teacher, I can't control myself, but you know the root cause is the school culture?
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A mouth that's liable to get loud and say to much at anytime.
by Mr. Terrence L. Trezvant October 13, 2003
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