Top definition
When you clear your inbox out completely, and start from scratch, or clean out all unwanted emails, spam, and the after effects of replyarrhea.
Dude 1: "Man, I accidentally checked all the email update boxes when I edited my facebook settings."

Dude 2: "You need an inbox colonoscopy."
by GabrielleWithoutWings November 08, 2009
Mug icon

The Urban Dictionary Mug

One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.

Buy the mug