1 definition by GabrielleWithoutWings

Top Definition
When you clear your inbox out completely, and start from scratch, or clean out all unwanted emails, spam, and the after effects of replyarrhea.
Dude 1: "Man, I accidentally checked all the email update boxes when I edited my facebook settings."

Dude 2: "You need an inbox colonoscopy."
by GabrielleWithoutWings November 08, 2009

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