Top Definition
A situation in which without taking Immodium, you will almost certainly shit yourself. Examples include situations of fear, embarrassment or extreme laughter in which you lose control over your bowels.
Man, I wish I popped an immodium because I diarrhea'd all over myself and the audience while walking the tightrope. That was true immodium challenge.
by matlin September 16, 2007
5 Words related to Immodium Challenge

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