Top Definition
ISMO stands for "it stresses me out"
that person talks about nothing!, ISMO!

i have so much shit to do today. Ismo.

"Are you stressed out

"Yes, ISMO!"
by RileyereksonAK August 19, 2011
The nickname given to people who will in the future, reach the pinnacle of success. Can also be used as a verb.
Noun- That Ismo is so much better than you are.

Verb- I'm gonna Ismo it up a bit. I need that A on this test.
by LAMS101 November 22, 2009

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