Top definition
A blending of holla and what's up. As a noun, a hussup describes a possible holla situation. One can hussup, meaning to holla at a young lady. One can use it in the form of a question such as: hussup girl?
Yo I'm about to bust a hussup girl on that ho.
She's definitely a hussup.
by KyleTheMan621 May 20, 2007
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