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1. To decapitate someone using a moving vehicle.

2. To sabotage someone

3. To be totally inebriated
1. When I stuck my head in her car to say hello she rolled the window up and hit the gas nearly hupsmuckering me.

2. You really hupsmuckered me by giving away the ending to my story.

3. Let go to the bar and get hupsmuckered.
by voglein June 19, 2011