a word used to describe a best friend from home, or 'a brother/sister from another mother - originates from canada.
Natalie your like totally my homeslice :)
by mblockgirls February 18, 2009
Homeslice= Slice of home
ur pal, bud, buddy, old friend (reminds u of ur childhood), brotha from anotha motha
-sometimes referred to as a type of greeting,
"yo homeslice whats happn'?!"
"Homeslice!"
by bekskie January 15, 2008
1. Word white people (such as myself) use in place of nigga. In order not to avoid confrontation from crowds of black males wanting to kill whitey. Instead of "What up nigga?" we say "What is up homeslice."
2. White folk talk for nigga.
"Oh I say my homeslice, what is up?"
by D. Schwal April 30, 2005
1) a term used to describe everyone
2) a term used indicating what kind of potatoes you had for breakfast
3)a word used to imply relations with a celebrity
4) offered as a drug although it does not exist
"dude you want some homeslice?"

"yea bro hook a brutha up"

"sucks for you cus it doesnt exist"
by slipknotmaGGot April 28, 2009
A slice of one's home.
"Hey my home's running kind of low on space"
"Here, just borrow a homeslice"
by Casey Patton January 11, 2008
Used to address one of your close friends and/or buddies.
yo! whazzup, homeslice?
yeah, jakes my homeslice.
by the samm April 25, 2007
a homie the bestest ones in life
Joe:heyy homeslice wats poppin?1
Paul:Nothing much my og wats up with u!?
by [og]lifee March 22, 2007

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