Top Definition
Having an unbelievably large colon, due to defective Indian Hedgehog gene expression.
Also known as megacolon.
Treated by the "pull-through" procedure, or the "endorectal pull".
Johnny's such a Hirshprung---have you checked out the size of that colon?

You know what they say about big Hirshprung's--big colon!
by Brasna November 18, 2010
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