1) Developing an aching wrist from playing too much of popular video game, Guitar Hero.
2) Proof that you have too much spare time.
Steve: Aaah!
Josh: What?
Steve: Hero's wrist...
Josh: Nerd.
by ohhowswish February 17, 2009
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where you have been playing guitar hero so long that your wrist gets mangled and deformed
"dude you have been playing guitar hero for a while, you might get guitar hero wrist!"

"what the hell, my wrist is all mangled and deformed!!!!"

"told you so..."
by oscar + jake December 30, 2006
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