Dry skin that flakes or peels off the hands.
Using harsh cleaners without wearing gloves can result in handruff.
by Ouroboros kitty June 25, 2007
Top Definition
The state in which your hands are excessively dry and skin peels off, similar to dandruff.
"Man, put some lotion on you have total handruff."
by AriaK January 05, 2010
When the palms of a person's hands are so dry that they leave a what looks like dandruff on what ever they touch.
My golf in structor, Scott, gets his handruff all over me. I have to shower twice to get it all off!
by FutureUSOpenChamp November 03, 2011
Free Daily Email

Type your email address below to get our free Urban Word of the Day every morning!

Emails are sent from daily@urbandictionary.com. We'll never spam you.