To take up a firearm against a political candidate or position you disagree with. Coined by the media in response to perceived violent rhetoric in the 2010 election campaigns. A variant on Senate candidate Sharron Angle's assertion during a debate that her opponent, incumbent senator Harry Reid, needed to "man up."
"Sure, the Republican­s use homophobia to "gun up" thier base but it's not working very well any more, the noticeable exception being old people." - David Brock, CEO of Media Matters of America, on Hardball with Chris Matthews, January 12, 2011
by The Mind of Matt January 15, 2011
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Something one says, when it's all tied up, crunch time, or the final moments of a competition.

-It is said to rev one or one’s team up

-It is also said ironically to acknowledge that the individual, whom said it, is about to be cluster!@#$ed.
Steve: Ah crap, it’s 3-3 in Search and Destroy…

Ryan: Guns up, let's do this
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Trevor: We’ve had 3 months to do this project, we haven’t started, and it’s due tomorrow…

Bradley: Alright, we got this on lock. Guns up, let's do this

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7’ Tall Angry, Black Man on PSP: You DID NOT just say, what I think you said white boy…!

Grant: *soils himself* Oh geez…, well… Guns up, let's do this
by Kittyburner506 July 9, 2010
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