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1.
A goofy noise made in the throat that denotes excitement, agreement or greeting.
"Marys here! *Gugh*" "Thats an awesome Idea Chuck, *Gugh*"
by TheTrinity October 23, 2005
 
2.
When the sigh ugh isn't enough. Sometimes you have to let out more than a typical ugh.
You're on the couch and your mom says "Can you go pick me up some milk?" All you can say is "Gugh!"
by dayummm.......... August 18, 2012