Top Definition
The act of going to the guadalupe river, renting toobs, drinking lots of beer, and hooking up with the opposite sex.
Matthew McConaughey: Hey man what are you doing this weekend?

Lance Armstrong: Dude, I'm headin to New Braunfels to get guadalupified.

Matthew McConaughey: Right on, Right on.
#river #guadalupe #gruene #new braunfels #tubes #rafts
by Playmaker16 September 02, 2010
6 Words related to Guadalupified
The condition of having had sex with a dirty Mexican.
After Playing Yu-gi-oh, Ashley was severely Guadalupified.
by Brian Varvaro May 10, 2005
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