To be under the extreme influence of methamphetamine. Typically the variety made in basements and by mountain people. Refers to the glossy condition of the eyes while using, similar to the term glossed when referring to alcohol.
-Did you see Jon at the party?

-Ya, he was Glessed out of his mind. He must have just come from his Mom's trailer.
by tortfeasor1 March 08, 2011

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