To be obliterated, annihilated, raped*, emasculated, or otherwise beaten, typically in a video game, in such a phenomenal way as to be comparable to the manner in which Gendo Ikari, a godlike character from the popular anime Neon Genesis Evangelion, would "own" someone (most commonly Shinji Ikari).

*can also be applied to literal/statutory rape, as in the case of Rei Ayanami.
1.
Player 1: Yeah motherfucker, you just got Gendowned.
Player 2: I just suck at fighting games.
by Orpheus II July 15, 2006
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