A self-inflicted developmental disabilty of millenials, caused by chronic digital media addiction, and characterized by short attention span, quick frustration, indiscipline, fatigue, and inability to absorb verbal information.
Doctor: I'm diagnosing you with game brain, probably caused by 2,000 hours of World of Warcraft, and exacerbated by 1,000 hours of GTA. I'm writing you a prescription for methadone. With treatment, you may one day be a person again.
by a j a x March 15, 2017
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the act of receiving a blow job while playing X-Box 360 or PS3
Dude, my girlfriend gave me game brain while i pwned in COD4.
by The Unknown Pseudonym May 12, 2009
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pregame brain is oral sex a guy recieves from a slut or friend with benifits before he gets his crazy night on and poppin.
Whoa girl, you gonna hook me up with some pregame brain?
by tai November 13, 2004
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To receive oral sex as an artistic pleasure from a woman.
Dude I'm telling you, she gets an "A" on her brain game!
by Jake Snakey January 5, 2007
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