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1.
Using Alcohol to help the process of getting ass at the end of the night.

Game Genie is to Nintendo as Alcohol is to Hooking Up.
Mike: How was your night?
Chris: Great, I got a steak dinner and I didn't even have to use Game Genie.
Mike: Real Nice!

Chris: You gonna try and hook up with that girl?
Mike: Yeah, but I think I'm going to have to Game Genie that first.
by Mordac, Lord of Unholy Fury August 09, 2006
 
2.
A product made by Camerica/Galoob for the NES, SNES, Genesis, Game Boy, and Game Gear. It manipulated the binary code to do some shit, I don't really know.
*Eunuch with effeminate voice* Hey! Yo! I totally broke through and hacked up Super Mario Brothers number one with my Game Genie!
*Straight guy* Wow! I just hacked into my girlfriend and now I have a son!
*Eunuch* I wish I had balls...
by Garfield135 November 23, 2008