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Acronym for "George Washington University," an institution of higher education located in Washington, DC founded in 1821. Can also represent "Gay White University," a parody commenting on the predominantly white and homosexual tendency of many students at the same school. Also often parodied as "GW Jew" referring to the disproportionate number of Jewish students at the school.
Effeminate White Male: "Girlfriend, please. He is as queer as a three-dollar bill. You know why they call this GWU? 'Gay White University!' Hello!"

or

Gentile: "Man, there are so many JAPs at this school. No wonder why they call it GW Jew."
by JohnQPublic March 24, 2007
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