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1.
Short for Good People For Life; describes an awesome person who's the epitome of perfect.
Chris: did you see that awesome episode of Out of the Box?
John: yeah. Tony's totally a GPFL.
by Sshaw101 April 28, 2013
 
2.
GPFL is an accronym for gangster pals for life.
hey gpfl whats up?
by jamgrb June 05, 2010