Top Definition
A syndrome that effects women who are overweight and have fat that surrounds their upper body near the breasts and back area. When they wear a bra, it will push fat out underneath the bra and will result in two "tits" in the back, thus resulting in the "4th tit syndrome"
Guy 1: "Yeah I was going to hook up with that chick at the frat party until I saw her back..."

Guy 2: "What was wrong with it?"

Guy 1: "Dude, she had fourth tit syndrome!"

Guy 2: "oooh.. yeah... that does suck "
by chunkymonkey99 February 08, 2010
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