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1.
Acronym for "Fuck A Fruit Basket", a term originating from Toronto, ON, Canada, and coined by the Progressive rock band Day Job Orchestra. It is primarily used a filler for random dialogue, often used to end a sentence and/or awkward situation. it can often have many defintions, and is open to interpretation...
When all else fails, FAFB!

I have a business installing Styrofoam nuns, FAFB!

one can have sexual intercourse with laundry basket that is full of food high in Vitamin C and other juice related products, or you could simply say FAFB!
by djsemat May 29, 2010
 
2.
F*cked again from behind. Derived from the initails for Fairchild Air Force Base, WA, known for screwing over it's aircraft maintainers. Further expansion brings in the state initials: F*cked again from behind, Without Astroglide
Crew Chief #1: "I've only been here a month, and they're already deploying me for 120 days"
Crew Chief #2: "Welcome to FAFB"
by Wrenchmonkey August 11, 2005
 
3.
someone who has no ass and a fat back.
Kristen tart is such a FAFB.
by ghgkhgkj January 31, 2009