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1.
A disease causing the condition of mononucleosis (aka mono), which is severe sore throat, fever and an enlarged spleen. It is often referred to as the "kissing disease". It is transferred from saliva, so one can get it from kissing, or sharing drinks. It is a herpes virus, same as the chicken pox (herpes zoster). This often occurs in children, but can also come up in adults. You can treat the symptoms, but the virus will always be in your system.
Yeah, so my girls got mono man. Who's she been kissing?

Yeah, so I've got Epstein-Barr after making out with her. Way to go!
by The AlliCat January 09, 2010
 
2.
A virus that many musicians and singers use as an excuse for canceling concert performances.
Brandon Flowers complained of his Epstein Barr and had to cancel a show.
by Nicole F June 02, 2007