Top Definition
Duff Delish refers to "a good buzz" or a "really good time". Specifically refers to a drinking/going out/drug buzz. "Duff" refers to being under the influence of substances and "delish" means a nice taste. Has become rather popular around Dublin, Ireland recently.
Chris: What was last night like?
Ronan: I was on such a duff delish, best night of my life.
by bigduffer February 24, 2010

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