A dumbass who gives thumbs down on a perfectly good Urban Dictionary definition. Most downers can be found on the main page where the word of the day is located. And there are quite a few of them.
What the hell?! I got 500 thumbs up and 2000 thumbs down! Buncha fuckin' downers!
by TheSaltyWhore February 19, 2011

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Somebody with down syndrome.
'Man, look at that guy, he's a massive downer!'
by 1128 June 11, 2007

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1. abbreviated from down-syndrome

2. more commonly used to describe someone who appears and acts like a spastic and is either extremely retarded or un-co
bob is a lazy eyed downer who deserves to be shot
by Hugh_11 September 27, 2005

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Someone who suffers from the ever popular "Syndrome of a Down". Usually sports a hideously deformed face and torso, crooked almond eyes and drools constantly. Known for ruining innocent, unsuspecting couples' lives with thier selfishness, they are generally an embarrassment to their families. They generally meander around causing unnecessary noise and offending people with their mere existence in cases where "too-nice-for-their-own-good" families have decided not to abort them or throw them to the wolves shortly after birth.
"That dude's a downer - notice the almond shaped eyes, hunched back and pulsating tongue, complete with an incessant flow of drool. Where's the shotgun?"
by Jes O'Briar March 10, 2008

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What extreme System of a Down fans call themselves. Most likely because they are the most kick ass band out there.
Slipknot fans are maggots, System fans are downers.

Tom: Dude I love SOAD.

Jim: You're such a downer.
by beanerwithaweiner June 29, 2006

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drugs that are depressants. Drugs like weed.
druggie:"Do you have any uppers"
dealer:"No man only downers."
druggie:*"well when can I see mary jane? I wanna take her on a cheap date."
Last sentence is code for, do you have any weed for cheap.?
by Insane February 07, 2004

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Often used in central London and suburban areas for describing not only the side effects of certain drugs, but also an emotional state. Downers, a most versatile word, can be used for a multitude of purposes.
That guy is on the downers.
Your so downers.
this is downers, whens the next train?
your mum is so downers.
Your sexual preferences are on the D (shortened illiteration).
by Jambowana May 31, 2005

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