That stage in the night at which you've had too much to drink, partied too hard, danced too much, or drank that one spirit that really puts you on a downer. The syndrome can often be amplified if the patient is going through some sort of trauma or difficulty in his or her (sober) life. The sufferer will also attempt to start deep, meaningful conversations with friends or even unknown passers by, spilling out his or her emotions in an attempt to solve his or her problems. This is usually followed by regret the next morning.
some are more prone than others.
Robert: Hey, why's Joe slumped in his chair, not talking to anyone, on his phone (again)?
Laura: ooohh...yeah I forgot to tell you something about Joe...he's got Down Syndrome. Stay well clear of him.
by joeiles August 31, 2008
Get the Down Syndrome mug.
If you buy unlimited cash on 2 Player Super Hero Tycoon on Roblox (not that I like the game or anything... totally hate it...)
Hey, how much cash u got on 2 Player Super Hero Tycoon?

I bought the unlimited cash game pass for 500 Robux.

BRUUUUUH stop having Down Syndrome and grow some balls -.-
Get the Down Syndrome mug.
When you have a syndrome where you like to lie down a lot.
Seriously, who thought it was a genetic disorder??? Y'all as stupid as a football player in a marching band.
Ok, if I really have to write an example, here goes nothing...
Micycle: Do you see him, an intellectual, over there? Why is he lying down???
Vladimir Putin: Yes he has Down Syndrome.
Micycle: You mean where he likes to lie down a lot?
Putin: Yes.
Him, an intellectual: I LAY
by AB365 December 19, 2017
Get the Down Syndrome mug.
a chromosomal (big word for smart people) disorder which effects someone for they're whole life. They have swollen looking eyes and difficulty with learning. they can also be insanely strong, i know a little girl with down syndrome, she is 9 and she can push an 80kg man to the ground. no problems. good thing is, they are very very nice people and generally more fun and outgoing than most of the nerds who will read this XD.

in short, if you call someone who did something stupid 'a downy' or 'down syndrome' you obviously don't know anyone who has it or have ever properly met someone who has it.
me: my little brother has down syndrome, what do u think of that?

normal person: id like to meet him, i don't know what to make of people with DS.

me: not many people do, you will love him. think jim carrey, just 11 and shorter

normal person: haha sounds good =)
by DS Rep. August 3, 2008
Get the down syndrome mug.
a person that assumes everyone owes him something. Even though he contributes nothing he believes he needs a share. He believes he is the sole proprietor of life. Uses the ability a broad does to put people in trances and snakes his way into your wallet.

downing syndrome; when throwing down on large purchases "oh i forgot my wallet" or "oh i only have my checkbook" or "oh the banks closed"
That guy has downing syndrome.

by hotchick 200 June 29, 2008
Get the downing syndrome mug.
you guys are all assholes sayin that stuff bout down syndrome....down syndrome is a form of mental retardation that causes you to learn slower and usually some of your physical features are different. They can be rather high functioning or non.
people with down syndrome can be very nice.
by Anonymous June 16, 2004
Get the down syndrome mug.