Top Definition
Stuck on something that puzzles you, or does not make sense to you, so much that it messes with your mind;
Or
Messed, ratty, looking confused and unorganized
I'm just disfuzzled by your explanation, it's so ridiculous!
Or
What did you just roll out of bed? You look disfuzzled!
by Curiouslacuna August 30, 2009
1 more definition
all messed up or not rite.
yo dog you look all disfuzzled today.
by timmy,kyle, and josh April 20, 2008

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