A game that children play where one child acts as the Disease Fly. The other children build a fort with blankets on a bed. The Disease Fly kid must try and break his/her way into the fort and get inside to disease the other kids. If the Fly gets in, the Disease Fly wins. The defending kids generally never win, it's just how long they can last.
Hey Kevin, do you wanna play Disease Fly? I'll be the fly today.
by TheDiseaseFly February 4, 2021
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The condition that a human fly suffers from.
Damn, you'd think she'd leave me alone after I rejected her 10 years ago.

Maybe she has human fly disease?
by humanflymagnet February 9, 2010
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