A destiple is a fan of the lead singer of the rock group r.e.m., Michael Stipe. These fanatics are so devoted to the lyrics (however indecipherable) written by Michael Stipe, that they worship him like he was Jesus or something. They often wonder what he's really like - since they'll never know - and delight in ridiculous anecdotes about him performing ordinary everyday tasks like opening his mail or talking on the phone.
Destiple: Awe! I bet Michael was adorable and sexy when he opened his mail!
Normal person: You need to get a life.